Dr. rer. nat. Birgit Knebel

Ausgewählte Publikationen

• Knebel B, Fahlbusch P, Dille M, Wahlers N, Hartwig S, Jacob S, Kettel U, Schiller M, Herebian D, Koellmer C, Lehr S, Müller-Wieland D, Kotzka J 2019. Fatty Liver Due to Increased de novo Lipogenesis: Alterations in the Hepatic Peroxisomal Proteome. Front Cell Dev Biol. 7. https://doi.org/10.3389/fcell.2019.00248
• Knebel B, Fahlbusch P, Poschmann G, Dille M, Wahlers N, Stühler K, Hartwig S, Lehr S, Schiller M, Jacob S, Kettel U, Müller-Wieland D, Kotzka J 2019. Adipokinome Signatures in Obese Mouse Models Reflect Adipose Tissue Health and Are Associated with Serum Lipid Composition. Int J Mol Sci. 20. https://doi.org/10.3390/ijms20102559
• Knebel B, Göddeke S, Hartwig S, Hörbelt T, Fahlbusch P, Al-Hasani H, Jacob S, Köllmer C, Kettel U, Schiller M, Lehr S, Kotzka J 2018. Alteration of Liver Peroxisomal and Mitochondrial Functionality in the NZO Mouse Model of Metabolic Syndrome. Proteomics Clin Appl. 12. https://doi.org/10.1002/prca.201700028
• Knebel B, Hartwig S, Jacob S, Kettel U, Schiller M, Passlack W, Koellmer C, Lehr S, Müller-Wieland D., Kotzka J 2018. Inactivation of SREBP-1a phosphorylation prevents fatty liver disease in mice: identification of related signaling pathways by gene expression profiles in liver and proteomes of peroxisomes. Int J Mol Sci. 19. https://doi.org/10.3390/ijms19040980
• Knebel B, Mack S, Haas J, Herman-Friede MK, Lange S, Schubert O, Kotzka J, Muller-Wieland D 2016. Divergent phenotypes in siblings with identical novel mutations in the HNF-1α gene leading to maturity onset diabetes of the young type 3. BMC Med Genet. 17. https://doi.org/10.1186/s12881-016-0297-z
• Knebel B, Strassburger K, Szendroedi J, Kotzka J, Scheer M, Nowotny B, Müssig K, Lehr S, Pacini G, Finner H, Klüppelholz B, Giani G, Al-Hasani H, Roden M for the GDS Group 2016. Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes. J Clin Endocrinol Metab. 101: 2130-40. https://doi.org/10.1210/jc.2015-4133
• Knebel B, Hartwig S, Haas J, Lehr S, Goeddeke S, Susanto F, Bohne L, Jacob S, Köllmer C, Nitzgen U, Müller-Wieland D, Kotzka J 2015. Peroxisomes compensate hepatic lipid overflow in mice with fatty liver. BBA Molecular and Cell Biology of Lipids. 1851: 965-76. https://doi.org/10.1016/j.bbalip.2015.03.003
• Knebel B, Kotzka J, Lehr S, Hartwig S, Avci H, Jacob S, Nitzgen U, Schiller M, März W, Hoffmann MM, Seemanova E, Haas J, Müller-Wieland D 2013. A mutation in the c-fos gene associated with congenital generalized lipodystrophy. Orphanet J Rare Dis. 8. https://doi.org/10.1186/1750-1172-8-119
• Knebel B, Haas J, Hartwig S, Jacob S, Köllmer C, Nitzgen U, Muller-Wieland D, Kotzka J 2012. Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass. PLOS ONE. 7. https://doi.org/10.1371/journal.pone.0031812