Selected Publications
- Nikolic A, Fahlbusch P, Wahlers N, Riffelmann N-K, Jacob S, Hartwig S, Kettel U, Dille M, Al-Hasani H, Kotzka J, Knebel B 2023. Chronic stress targets mitochondrial respiratory efficiency in the skeletal muscle of C57BL/6 mice. Cell Mol Life Sci. 80. https://doi.org/10.1007/s00018-023-04761-4
- Fahlbusch P, Nikolic A, Hartwig S, Jacob S, Kettel U, Köllmer C, Al-Hasani H, Lehr S, Müller-Wieland D, Knebel B, Kotzka J 2022. Adaptation of Oxidative Phosphorylation Machinery Compensates for Hepatic Lipotoxicity in Early Stages of MAFLD. Int J Mol Sci. 23. https://doi.org/10.3390/ijms23126873
- Dille M, Nikolic A, Wahlers N, Fahlbusch P, Jacob S, Hartwig S, Lehr S, Kabra D, Klymenko O, Al-Hasani H, Kotzka J, Knebel B 2022. Long-term adjustment of hepatic lipid metabolism after chronic stress and the role of FGF21. BBA Molecular Basis of Disease. 1868. https://doi.org/10.1016/j.bbadis.2021.166286
- Barbosa DM, Fahlbusch P, Herzfeld de Wiza D, Jacob S, Kettel U, Al-Hasani H, Krüger M, Ouwens DM, Hartwig S, Lehr S, Kotzka J, Knebel B 2020. Rhein, a novel Histone Deacetylase (HDAC) inhibitor with antifibrotic potency in human myocardial fibrosis. Sci Rep. 10. https://doi.org/10.1038/s41598-020-61886-3
- Knebel B, Müller-Wieland D, Kotzka J 2020. Lipodystrophies-Disorders of the Fatty Tissue. Int J Mol Sci. 21. https://doi.org/10.3390/ijms21228778
- Knebel B, Fahlbusch P, Poschmann G, Dille M, Wahlers N, Stühler K, Hartwig S, Lehr S, Schiller M, Jacob S, Kettel U, Müller-Wieland D, Kotzka J 2019. Adipokinome Signatures in Obese Mouse Models Reflect Adipose Tissue Health and Are Associated with Serum Lipid Composition. Int J Mol Sci. 20. https://doi.org/10.3390/ijms20102559
- Knebel B, Fahlbusch P, Dille M, Wahlers N, Hartwig S, Jacob S, Kettel U, Schiller M, Herebian D, Koellmer C, Lehr S, Müller-Wieland D, Kotzka J 2019. Fatty Liver Due to Increased de novo Lipogenesis: Alterations in the Hepatic Peroxisomal Proteome. Front Cell Dev Biol. 7. https://doi.org/10.3389/fcell.2019.00248
- Knebel B, Hartwig S, Jacob S, Kettel U, Schiller M, Passlack W, Koellmer C, Lehr S, Müller-Wieland D., Kotzka J 2018. Inactivation of SREBP-1a phosphorylation prevents fatty liver disease in mice: identification of related signaling pathways by gene expression profiles in liver and proteomes of peroxisomes. Int J Mol Sci. 19. https://doi.org/10.3390/ijms19040980
- Knebel B, Strassburger K, Szendroedi J, Kotzka J, Scheer M, Nowotny B, Müssig K, Lehr S, Pacini G, Finner H, Klüppelholz B, Giani G, Al-Hasani H, Roden M for the GDS Group 2016. Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes. J Clin Endocrinol Metab. 101: 2130-40. https://doi.org/10.1210/jc.2015-4133
- Knebel B, Mack S, Haas J, Herman-Friede MK, Lange S, Schubert O, Kotzka J, Muller-Wieland D 2016. Divergent phenotypes in siblings with identical novel mutations in the HNF-1α gene leading to maturity onset diabetes of the young type 3. BMC Med Genet. 17. https://doi.org/10.1186/s12881-016-0297-z
- Knebel B, Hartwig S, Haas J, Lehr S, Goeddeke S, Susanto F, Bohne L, Jacob S, Köllmer C, Nitzgen U, Müller-Wieland D, Kotzka J 2015. Peroxisomes compensate hepatic lipid overflow in mice with fatty liver. BBA Molecular and Cell Biology of Lipids. 1851: 965-76. https://doi.org/10.1016/j.bbalip.2015.03.003
- Knebel B, Kotzka J, Lehr S, Hartwig S, Avci H, Jacob S, Nitzgen U, Schiller M, März W, Hoffmann MM, Seemanova E, Haas J, Müller-Wieland D 2013. A mutation in the c-fos gene associated with congenital generalized lipodystrophy. Orphanet J Rare Dis. 8. https://doi.org/10.1186/1750-1172-8-119
- Knebel B, Haas J, Hartwig S, Jacob S, Köllmer C, Nitzgen U, Muller-Wieland D, Kotzka J 2012. Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass. PLOS ONE. 7. https://doi.org/10.1371/journal.pone.0031812