Univ.-Prof. Dr. rer. nat. Eckhard Lammert

Selected Publications

• Scholz O, Huß E, Otter S, Herebian D, Hamacher A, Levy LM, Hristeva S, Sanz M, Ajani H, Puentes AR, Hoffmann T, Hogeback J, Unger A, Terheyden S, Reina do Fundo M, Dewidar B, Roden M, Lammert E 2023. Protection of pancreatic islets from oxidative cell death by a peripherally-active morphinan with increased drug safety. Mol Metab. 75. https://doi.org/10.1016/j.molmet.2023.101775
• Pelligra A, Mrugala J, Griess K, Kirschner P, Nortmann O, Bartosinska B, Köster A, Krupenko NI, Gebel D, Westhoff P, Steckel B, Eberhard D, Herebian D, Belgardt B-F, Schrader J, Weber APM, Krupenko SA, Lammert E 2023. Pancreatic islet protection at the expense of secretory function involves serine-linked mitochondrial one-carbon metabolism. Cell Rep. 42. https://doi.org/10.1016/j.celrep.2023.112703
• Henning C, Branopolski A, Follert P, Lewandowska O, Ayhan A, Benkhoff M, Flögel U, Kelm M, Heiss C, Lammert E 2021. Endothelial β1 integrin-mediated adaptation to myocardial ischemia. Thromb Haemostasis. 121: 741-754. https://doi.org/10.1055/s-0040-1721505
• Scholz O, Otter S, Welters A, Wörmeyer L, Dolenšek J, Klemen MS, Pohorec V, Eberhard D, Mrugala J, Hamacher A, Koch A, Sanz M, Hoffmann T, Hogeback J, Herebian D, Klöcker N, Piechot A, Mayatepek E, Meissner T, Stožer A, Lammert E 2021. Peripherally active dextromethorphan derivatives lower blood glucose levels by targeting pancreatic islets. Cell Chem Biol. 28: 1474-1488.e7. https://doi.org/10.1016/j.chembiol.2021.05.011
• Urner S, Planas-Paz L, Hilger LS, Henning C, Branopolski A, Kelly-Goss M, Stanczuk L, Pitter B, Montanez E, Peirce SM, Mäkinen T, Lammert E 2019. Identification of ILK as a critical regulator of VEGFR3 signalling and lymphatic vascular growth. EMBO J. 38. https://doi.org/10.15252/embj.201899322
• Lorenz L, Axnick J, Buschmann T, Henning C, Urner S, Fang S, Nurmi H, Eichhorst N, Holtmeier R, Bódis K, Hwang J-H, Müssig K, Eberhard D, Stypmann J, Kuss O, Roden M, Alitalo K, Häussinger D, Lammert E 2018. Mechanosensing by β1 integrin induces angiocrine signals for liver growth and survival. Nature. 562: 128-132. https://doi.org/10.1038/s41586-018-0522-3
• Kragl M, Schubert R, Haiko K, Otter S, Bartosinska B, Jeruschke K, Weiß J, Chen C, Alsteens D, Kuss O, Speier S, Eberhard D, Müller DJ, Lammert E 2016. The biomechanical properties of an epithelial tissue determine the location of its vasculature. Nat Commun. 7. https://doi.org/10.1038/ncomms13560
• Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen MS, Stožer A, Wnendt S, Piemonti L, Köhler M, Ferrer J, Thorens B, Schliess F, Rupnik MS, Heise T, Berggren P-O, Klöcker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E 2015. Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment. Nat Med. 21: 363-72. https://doi.org/10.1038/nm.3822
• Konstantinova I, Nikolova G, Ohara-Imaizumi M, Meda P, Kucera T, Zarbalis K, Wurst W, Nagamatsu S, Lammert E 2007. EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets. Cell. 129: 359-70. https://doi.org/10.1016/j.cell.2007.02.044
• Lammert E, Cleaver O, Melton D 2001. Induction of pancreatic differentiation by signals from blood vessels. Science (New York, N.Y.). 294: 564-7. https://doi.org/10.1126/science.1064344