Melanie Mittenbühler, Dr.

Selected Publications

• Mittenbühler M, Smythers AL, Spiegelman BM 2024. Proteomic profiling of extracellular fluids to identify secreted proteins from muscle and fat tissues. Methods Cell Biology. https://doi.org/doi.org/10.1016/bs.mcb.2024.08.004
• Mittenbühler MJ, Jedrychowski MP, Van Vranken JG, Sprenger H-G, Wilensky S, Dumesic PA, Sun Y, Tartaglia A, Bogoslavski D, A M, Xiao H, Blackmore KA, Reddy A, Gygi SP, Chouchani ET, Spiegelman BM 2023. Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues. Cell metabolism. 35: 535-549.e7. https://doi.org/doi.org/10.1016/j.cmet.2022.12.014
• Mittenbühler MJ, Saedler K, Nolte H, Kern L, Zhou J, Qian S-B, Meder L, Ullrich RT, Brüning JC, Wunderlich FT 2020. Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo. Molecular Metabolism. 42: 101085. https://doi.org/doi.org/10.1016/j.molmet.2020.101085
• Mittenbühler MJ, Sprenger H-G, Gruber S, Wunderlich CM, Kern L, Brüning JC, Wunderlich FT 2018. Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma. Molecular Metabolism. 17: 122-133. https://doi.org/doi.org/10.1016/j.molmet.2018.08.010