Univ.-Prof. Dr. rer. nat. Hadi Al-Hasani

Selected Publications

• Stermann T, Menzel F, Weidlich C, Jeruschke K, Weiß J, Altenhofen D, Benninghoff T, Pujol A, Bosch F, Rustenbeck I, Ouwens M, Thoresen GH, de Wendt C, Lebek S, Schallschmidt T, Kragl M, Lammert E, Chadt AS, Al-Hasani H 2018. Deletion of the RabGAP TBC1D1 leads to enhanced insulin secretion and fatty acid oxidation in islets from male mice. Endocrinology. 159: 1748-1761. https://doi.org/10.1210/en.2018-00087
• Schallschmidt T, Lebek S, Altenhofen D, Damen M, Schulte Y, Knebel B, Herwig R, Rasche A, Stermann T, Kamitz A, Hallahan N, Jähnert M, Vogel H, Schürmann A, Chadt A, Al-Hasani H 2018. Two Novel Candidate Genes for Insulin Secretion Identified by Comparative Genomics of Multiple Backcross Mouse Populations. Genetics. 210: 1527-1542. https://doi.org/10.1534/genetics.118.301578
• Mafakheri S, Flörke RR, Kanngießer S, Hartwig S, Espelage L, De Wendt C, Schönberger T, Hamker N, Lehr S, Chadt A, Al-Hasani H 2018. AKT and AMPK regulate TBC1D1 through phosphorylation and its interaction with the cytosolic tail of insulin-regulated aminopeptidase IRAP. J Biol Chem. 293: 17853-17862. https://doi.org/10.1074/jbc.RA118.005040
• Knebel B, Strassburger K, Szendroedi J, Kotzka J, Scheer M, Nowotny B, Müssig K, Lehr S, Pacini G, Finner H, Klüppelholz B, Giani G, Al-Hasani H, Roden M for the GDS Group 2016. Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes. J Clin Endocrinol Metab. 101: 2130-40. https://doi.org/10.1210/jc.2015-4133
• Chadt A, Immisch A, de Wendt C, Springer C, Zhou Z, Stermann T, Holman GD, Loffing-Cueni D, Loffing J, Joost H-G, Al-Hasani H 2015. Deletion of both Rab-GTPase-activating proteins TBC14KO and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport. Diabetes 2015;64:746-759. Diabetes. 64: 1492. https://doi.org/10.2337/db15-er04
• Dreja T, Jovanovic Z, Rasche A, Kluge R, Herwig R, Tung Y, Joost H-G, Yeo GSH, Al-Hasani H 2010. Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model of the metabolic syndrome. Diabetologia. 309–320. https://doi.org/10.1007/s00125-009-1576-4
• Wuschke S, Dahm S, Schmidt C, Joost H-G, Al-Hasani H 2007. A meta-analysis of quantitative trait loci associated with body weight and adiposity in mice. Int J Obes. 31: 829–841. https://doi.org/10.1038/sj.ijo.0803473
• Al-Hasani H, Hinck CS, Cushman SW 1998. Endocytosis of the glucose transporter GLUT4 is mediated by the GTPase dynamin. J Biol Chem. 273: 17504-10. https://doi.org/doi: 10.1074/jbc.273.28.17504