Dr. rer. nat. Bengt-Frederik Belgardt, Dipl. Biol.
Deputy Director
Institute for Vascular and Islet Cell Biology
Head
Research Group Beta Cell Defects
+49 211 3382-451
Selected Publications
- Griess K, Rieck M, Müller N, Karsai G, Hartwig S, Pelligra A, Hardt R, Schlegel C, Kuboth J, Uhlemeyer C, Trenkamp S, Jeruschke K, Weiss J, Peifer-Weiss L, Xu W, Cames S, Yi X, Cnop M, Beller M, Stark H, Kondadi AK, Reichert AS, Markgraf D, Wammers M, Häussinger D, Kuss O, Lehr S, Eizirik D, Lickert H, Lammert E, Roden M, Winter D, Al-Hasani H, Höglinger D, Hornemann T, Brüning JC, Belgardt B-F 2023. Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis. Nat Cell Biol. 25: 20–29 . https://doi.org/10.1038/s41556-022-01027-2
- Uhlemeyer C, Müller N, Rieck M, Kuboth J, Schlegel C, Grieß K, Dorweiler TF, Heiduschka S, Eckel J, Roden M, Lammert E, Stoffel M, Belgardt B-F 2023. Selective ablation of P53 in pancreatic beta cells fails to ameliorate glucose metabolism in genetic, dietary and pharmacological models of diabetes mellitus. Mol Metab. 67. https://doi.org/10.1016/j.molmet.2022.101650
- Uhlemeyer C, Müller N, Grieß K, Wessel C, Schlegel C, Kuboth J, Belgardt B-F 2020. ATM and P53 differentially regulate pancreatic beta cell survival in Ins1E cells. PLOS ONE. 15. https://doi.org/10.1371/journal.pone.0237669
- Carstensen-Kirberg M, Röhrig K, Niersmann C, Ouwens DM, Belgardt BF, Roden M, Herder C 2019. Sfrp5 increases glucose-stimulated insulin secretion in the rat pancreatic beta cell line INS-1E. PLOS ONE. 14. https://doi.org/10.1371/journal.pone.0213650
- Belgardt B-F, Jarasch A, Lammert E 2018. Exploring biological and social networks to better understand and treat diabetes mellitus: Comment on "Network science of biological systems at different scales: A review" by Gosak et al. Phys Life Rev. 24: 146-148. https://doi.org/10.1016/j.plrev.2017.12.004
- Belgardt B-F, Lammert E 2016. DYRK1A: A Promising Drug Target for Islet Transplant-Based Diabetes Therapies. Diabetes. 65: 1496-8. https://doi.org/10.2337/dbi16-0013
- Belgardt B-F, Ahmed K, Spranger M, Latreille M, Denzler R, Kondratiuk N, von Meyenn F, Villena FN, Herrmanns K, Bosco D, Kerr-Conte J, Pattou F, Rülicke T, Stoffel M 2015. The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes. Nat Med. 21: 619-27. https://doi.org/10.1038/nm.3862